Class Effect Unveiled: PPARγ Agonists and MEK Inhibitors in Cancer Cell Differentiation

Epithelial-to-mesenchymal transition (EMT) plays a major role in breast cancer progression and the development of drug resistance. We have previously demonstrated a trans-differentiation therapeutic approach targeting invasive dedifferentiated cancer cells. Using a combination of PPARγ agonists and...

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Detalhes bibliográficos

Principais autores:	Rakefet Ben-Yishay, Opher Globus, Nora Balint-Lahat, Sheli Arbili-Yarhi, Neta Bar-Hai, Vered Bar, Sara Aharon, Anna Kosenko, Adi Zundelevich, Raanan Berger, Dana Ishay-Ronen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-09-01
Colecção:	Cells
Assuntos:	breast cancer differentiation therapy PPARγ agonist thiazolidinediones MEK inhibitor EMT
Acesso em linha:	https://www.mdpi.com/2073-4409/13/17/1506
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