Development of high-throughput lacrimal gland organoid platforms for drug discovery in dry eye disease

Dysfunction and damage of the lacrimal gland (LG) results in ocular discomfort and dry eye disease (DED). Current therapies for DED do not fully replenish the necessary lubrication to rescue optimal vision. New drug discovery for DED has been limited perhaps because in vitro models cannot mimic the...

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Hlavní autoři:	Teerapat Rodboon, Supansa Yodmuang, Risa Chaisuparat, Joao N. Ferreira
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-04-01
Edice:	SLAS Discovery
Témata:	Dry eye disease Xerophthalmia Lacrimal gland Organoids Bioprinting Drug discovery
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2472555221000174
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