Inflammation and IL-4 regulate Parkinson’s and Crohn’s disease associated kinase LRRK2

Abstract Mutations in Leucine-Rich Repeat protein Kinase 2 (LRRK2) are associated with Parkinson’s disease (PD) and Crohn’s disease (CD), but the regulation of LRRK2 during inflammation remains relatively unexplored. Here we describe the development of a flow cytometry-based assay to assess LRRK2 ac...

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Xehetasun bibliografikoak
Egile Nagusiak:	Dina Dikovskaya, Rebecca Pemberton, Matthew Taylor, Anna Tasegian, Purbasha Bhattacharya, Karolina Zeneviciute, Esther M Sammler, Andrew J M Howden, Dario R Alessi, Mahima Swamy
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Springer Nature 2025-05-01
Saila:	EMBO Reports
Gaiak:	LRRK2 Crohn’s Disease Parkinson’s Disease B Cells Interleukin-4
Sarrera elektronikoa:	https://doi.org/10.1038/s44319-025-00473-x
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Inflammation and IL-4 regulate Parkinson’s and Crohn’s disease associated kinase LRRK2

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