Integrative omics analysis reveals insights into small colony variants of Staphylococcus aureus induced by sulfamethoxazole-trimethoprim

Abstract Background Long-term treatment with trimethoprim-sulfamethoxazole (SXT) can lead to the formation of small-colony variants (SCVs) of Staphylococcus aureus. However, the mechanism behind SCVs formation remains poorly understood. In this study, we explored the phenotype and omics-based charac...

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Detalles Bibliográficos

Principais autores:	Jingwen Zhou, Chunyan He, Han Yang, Wen Shu, Qingzhong Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-06-01
Series:	BMC Microbiology
Assuntos:	Small colony variant Staphylococcus aureus Genomics Transcriptomics Metabolomics Sulfamethoxazole-trimethoprim
Acceso en liña:	https://doi.org/10.1186/s12866-024-03364-8
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