A pre-vaccination immune metabolic interplay determines the protective antibody response to a dengue virus vaccine

Summary: Protective immunity to dengue virus (DENV) requires antibody response to all four serotypes. Systems vaccinology identifies a multi-OMICs pre-vaccination signature and mechanisms predictive of broad antibody responses after immunization with a tetravalent live attenuated DENV vaccine candid...

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Autori principali:	Adam-Nicolas Pelletier, Gabriela Pacheco Sanchez, Abdullah Izmirly, Mark Watson, Tiziana Di Pucchio, Karina Inacio Carvalho, Abdelali Filali-Mouhim, Eustache Paramithiotis, Maria do Carmo S.T. Timenetsky, Alexander Roberto Precioso, Jorge Kalil, Michael S. Diamond, Elias K. Haddad, Esper G. Kallas, Rafick Pierre Sekaly
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-07-01
Serie:	Cell Reports
Soggetti:	CP: Immunology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124724006983
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