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Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis.

Calcium can play an important role in the regulation of autophagy. We previously reported that exogenously introduced calcium in the form of calcium phosphate precipitates (CPP) induces autophagy. Here we showed that CPP-induced autophagy required the classical autophagic machinery, including the au...

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Autores principales: Xi Chen, Min Li, Daohong Chen, Wentao Gao, Jun-Lin Guan, Massaki Komatsu, Xiao-Ming Yin
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3528773?pdf=render
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