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Role of CTLA-4 blockade and dacarbazine therapy following anti-PD-1 resistance in melanoma

Abstract Many patients with advanced melanoma eventually stop responding to PD-1 immunotherapy, and effective treatments are limited. Recent studies suggest that older chemotherapy drugs such as dacarbazine and temozolomide may work better after prior PD-1 therapy and can stimulate the immune system...

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Hlavní autoři: Vincas Urbonas, Audrius Dulskas
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2026-03-01
Edice:Discover Oncology
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On-line přístup:https://doi.org/10.1007/s12672-026-04816-5
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