Dual Inhibition of the Renin–Angiotensin–Aldosterone System and Sodium–Glucose Cotransporter-2: Mechanistic and Clinical Evidence for Cardiorenal Protection

Overactivation of the renin–angiotensin–aldosterone system (RAAS) promotes haemodynamic overload, inflammation, and fibrosis in the heart and kidneys. Recently, sodium–glucose cotransporter-2 (SGLT2) inhibitors have emerged as a cornerstone therapy in cardiorenal protection. Emerging data indicate t...

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Bibliografiska uppgifter

Huvudupphov:	Reem F. M. Aazar, Rayan Arzouni, Persoulla A. Nicolaou
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2026-01-01
Serie:	Biomedicines
Ämnen:	renin–angiotensin–aldosterone system (RAAS) sodium glucose co-transporter inhibitors (SGLT2i) heart failure (HF) type 2 diabetes (T2D) angiotensin converting enzyme inhibitor (ACEI) angiotensin receptor blocker (ARB)
Länkar:	https://www.mdpi.com/2227-9059/14/1/101
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