Porphyrins with combinations of 4-carboxyphenyl and 4-hydroxyphenyl substituents in meso-positions as anti-HIV-1 agents

Abstract A series of 4-carboxyphenyl/4-hydroxyphenyl meso-substituted porphyrins were synthesized, purified, and characterized. The compounds exhibited anti-HIV-1 activities, in vitro, under both non-photodynamic (non-PDT) and photodynamic (PDT) conditions. Specifically, the porphyrins inhibited HIV...

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Hlavní autoři:	Debdulal Sharma, Aradhana Singh, Sanaullah Safi, Ritu Gaur, Devashish Sengupta
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-05-01
Edice:	Scientific Reports
Témata:	Porphyrins Photodynamic therapy Photoinactivation of viruses Photosensitizers
On-line přístup:	https://doi.org/10.1038/s41598-024-60728-w
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