Transcriptomic profiling reveals SARS-CoV-2-infected humanized MHC mice recapitulate human post vaccination immune responses

BackgroundThe ongoing COVID-19 pandemic caused by SARS-CoV-2 remains a critical global health priority, with persistent socioeconomic ramifications despite its reclassification from Public Health Emergency of International Concern (PHEIC) status. While humanized major histocompatibility complex (hMH...

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Detalhes bibliográficos

Principais autores:	Siyue Li, Xuelian Han, Ruolan Hu, Keyu Sun, Min Li, Yuan Wang, Guangyu Zhao, Mengzhe Li, Huahao Fan, Qi Yin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-08-01
Colecção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	hMHC mice SARS-CoV-2 COVID-19 Humanization Transcriptome
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1634577/full
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