Shigella effector IpaH1.4 subverts host E3 ligase RNF213 to evade antibacterial immunity

Abstract Ubiquitination plays vital roles in modulating pathogen-host cell interactions. RNF213, a E3 ligase, can catalyze the ubiquitination of lipopolysaccharide (LPS) and is crucial for antibacterial immunity in mammals. Shigella flexneri, an LPS-containing pathogenic bacterium, has developed mec...

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Hlavní autoři:	Xindi Zhou, Huijing Zhang, Yaru Wang, Danni Wang, Zhiqiao Lin, Yuchao Zhang, Yubin Tang, Jianping Liu, Yu-Feng Yao, Yixiao Zhang, Lifeng Pan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-04-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-58432-y
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