Evaluation of a 55-gene classifier as a prognostic biomarker for adjuvant chemotherapy in stage III colon cancer patients

Abstract Background Adjuvant chemotherapy reduces the risk of recurrence of stage III colon cancer (CC). However, more effective prognostic and predictive biomarkers are needed for better treatment stratification of affected patients. Here, we constructed a 55-gene classifier (55GC) and investigated...

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Autori principali:	Eiji Oki, Eiji Shinto, Mototsugu Shimokawa, Shigeki Yamaguchi, Megumi Ishiguro, Seiji Hasegawa, Yasumasa Takii, Hideyuki Ishida, Tetsuya Kusumoto, Masaru Morita, Naohiro Tomita, Manabu Shiozawa, Masafumi Tanaka, Heita Ozawa, Yojiro Hashiguchi, Shinobu Ohnuma, Sachiyo Tada, Tomoko Matsushima, Kazuo Hase
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2021-12-01
Serie:	BMC Cancer
Soggetti:	Colon cancer Predictive Adjuvant chemotherapy Oxaliplatin Subtyping
Accesso online:	https://doi.org/10.1186/s12885-021-09088-6
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