Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model.

Cancer cachexia (CC) is a multifactorial disease characterized by decreased food intake and loss of body weight due to reduced musculature with or without loss of fat mass. Patients with gastric cancer have a high incidence of cachexia. We previously established a novel CC rat model induced by human...

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Autores principales:	Kiyoshi Terawaki, Yohei Kashiwase, Yumi Sawada, Hirofumi Hashimoto, Mitsuhiro Yoshimura, Katsuya Ohbuchi, Yuka Sudo, Masami Suzuki, Kanako Miyano, Seiji Shiraishi, Yoshikazu Higami, Kazuyoshi Yanagihara, Tomohisa Hattori, Yoshio Kase, Yoichi Ueta, Yasuhito Uezono
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2017-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC5332064?pdf=render
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