PHGDH-mediated serine synthesis reduces oligodendrocyte death by sustaining GSH and NADPH levels after brain ischemia
IntroductionWhite matter is vulnerable to early ischemic injury. The susceptibility of oligodendrocytes to ischemic damage can lead to demyelination, axonal degeneration, and neurological deficits, making them a key focus for understanding and developing therapies for stroke-related brain injury. In...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
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Frontiers Media S.A.
2026-04-01
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| Collection: | Frontiers in Pharmacology |
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| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fphar.2026.1735477/full |
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