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Promethin Is a Conserved Seipin Partner Protein

Seipin (BSCL2/SPG17) is a key factor in lipid droplet (LD) biology, and its dysfunction results in severe pathologies, including the fat storage disease Berardinelli-Seip congenital lipodystrophy type 2, as well as several neurological seipinopathies. Despite its importance for human health, the mol...

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Principais autores: Inês G. Castro, Michal Eisenberg-Bord, Elisa Persiani, Justin J. Rochford, Maya Schuldiner, Maria Bohnert
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-03-01
Serier:Cells
Fag:
promethin
TMEM159
seipin
BSCL2
SPG17
lipid droplet
LD
lipodystrophy
LDO
adipogenesis
Online adgang:https://www.mdpi.com/2073-4409/8/3/268
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