Clerodendranthus spicatus [Orthosiphon aristatus (Blume) Miq.] maintains uric acid homeostasis via regulating gut microbiota and restrains renal inflammation in hyperuricemic nephropathy

IntroductionThe kidney damage caused by the deposition of uric acid in the kidneys is of urgent need for new treatment drugs due to its complex pathogenesis. Orthosiphon aristatus (Blume) Miq. Also known as C. spicatus, which has a significant therapeutic effect on hyperuricemia nephropathy (HN), ho...

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Hlavní autoři:	Yang Wang, Kaiwen Li, Siya Yan, Ge Li, Meifang Cheng, Qian Chen, Yuzheng Wu, Dan Wang, Tao Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-11-01
Edice:	Frontiers in Pharmacology
Témata:	Orthosiphon aristatus (Blume) Miq. hyperuricemic nephropathy gut microbiota renal fibrosis NLRP3 signaling pathway
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1485861/full
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