ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates

Abstract Adjuvants play an important role in modulating antigen-specific immune responses. We conducted a comparative adjuvant immunogenicity study in Rhesus macaques using HIV-1 subtype B gp120 envelope protein, B.63521, formulated with aluminum hydroxide gel (AH), or a family of liposomal adjuvant...

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Үндсэн зохиолчид:	Shikha Shrivastava, Joshua M. Carmen, Jiae Kim, Kristina K. Peachman, Shraddha Basu, Ryan Alving, Danielle Nettere, Gautam Kundu, Lauren Yum, Mohammad Arif Rahman, Shalini Jha, Hung V. Trinh, Lorean Rosado, Phuong Nguyen, Elaine Morrison, Isabella Swafford, Kawthar Machmach, Jessica S. Bolton, Adam Yates, Elina Misicka, Zoltan Beck, Simona Mutascio, Ousman Jobe, Michelle Zemil McCrea, Lindsay Wieczorek, Elke S. Bergmann-Leitner, Victoria Polonis, Dominic Paquin-Proulx, Justin Pollara, Gary R. Matyas, Carl R. Alving, Rasmi Thomas, Genoveffa Franchini, Guido Ferrari, Barton F. Haynes, Julie A. Ake, Mangala Rao
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-12-01
Цуврал:	npj Vaccines
Онлайн хандалт:	https://doi.org/10.1038/s41541-025-01322-7
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!