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Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication

During infection with dengue viruses (DENVs), the lipid landscape within host cells is significantly altered to assemble membrane platforms that support viral replication and particle assembly. Fatty acyl-CoAs are key intermediates in the biosynthesis of complex lipids that form these membranes. The...

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Main Authors: Laura A. St Clair, Stephanie A. Mills, Elena Lian, Paul S. Soma, Aritra Nag, Caroline Montgomery, Gabriela Ramirez, Nunya Chotiwan, Rebekah C. Gullberg, Rushika Perera
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
lipids
dengue virus
acyl-CoA
acyl-CoA thioesterase
fatty acids
membranes
Online Access:https://www.mdpi.com/1999-4915/14/2/240
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