Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni

The protozoan parasite Entamoeba histolytica can induce amebic colitis and amebic liver abscess. First-line drugs for the treatment of amebiasis are nitroimidazoles, particularly metronidazole. Metronidazole has side effects and potential drug resistance is a concern. Schistosomiasis, a chronic and...

Полное описание

Библиографические подробности

Главные авторы:	Alexandra Probst, Thi N. Nguyen, Nelly El-Sakkary, Danielle Skinner, Brian M. Suzuki, Frederick S. Buckner, Michael H. Gelb, Conor R. Caffrey, Anjan Debnath
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2019-05-01
Серии:	Frontiers in Cellular and Infection Microbiology
Предметы:	Entamoeba histolytica Schistosoma mansoni farnesyltransferase metronidazole lonafarnib tipifarnib
Online-ссылка:	https://www.frontiersin.org/article/10.3389/fcimb.2019.00180/full
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!