Signaling by intracellular β2-adrenergic receptors regulates AMPA receptor trafficking and synaptic plasticity

Summary: Signaling by norepinephrine (NE) via adrenergic receptors (ARs) mediates attention, yet the underlying molecular mechanisms are largely unknown. AMPA receptors (AMPARs) form a complex with β2ARs, Gs, adenylyl cyclase, and protein kinase A (PKA) to augment AMPAR phosphorylation and, thereby,...

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Principais autores:	Boram Lee, Xiaomin Xing, Erik A. Hammes, Zhuoer Zeng, Zoila M. Estrada-Tobar, Karam Kim, Kyle E. Ireton, Kwun Nok Mimi Man, Ariel A. Jacobi, Ruben A. Berumen, Justin C. Weiner, Ao Shen, Bing Xu, Joanne Wang, Paul J. Gasser, Manuel F. Navedo, Yang K. Xiang, Elva Díaz, Chao-Yin Chen, Mary C. Horne, Johannes W. Hell
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-08-01
Series:	Cell Reports
Assuntos:	CP: Neuroscience CP: Cell biology
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S221112472500782X
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