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Fully synthetic phosphorylated Tau181, Tau217, and Tau231 calibrators for Alzheimer’s disease diagnosis

BackgroundThe calibrator in immunoassay plays an essential role in diagnosing Alzheimer’s disease (AD). Presently, the most well-studied biomarkers for AD diagnosis are three phosphorylated Tau (p-Tau): p-Tau231, p-Tau217, and p-Tau181. Glycogen synthase-3beta (GSK3β)-phosphorated Tau-441 is the mos...

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Main Authors: Xinyu Li, Huimei Zeng, Pradeepraj Durairaj, Weihuan Wen, Tianpeng Li, Yanru Zhao, Yang Liu, Xue Liu, Lingpeng Zhan, Lang Rao, Wen Yuan, Tengfei Guo, Weijun Shen, Hui Cai, Zhicheng Chen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
Tau
calibrator
Simoa
diagnosis
immunoassay
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1340706/full
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