Mesenchymal stem cell-derived apoptotic extracellular vesicles loaded with Prussian blue nanoparticles attenuate severe acute pancreatitis via neutrophil extracellular traps resolution and acinar-ductal metaplasia promotion

Abstract Nowadays, severe acute pancreatitis (SAP) remains a critical clinical disease with a high mortality rate. Current treatments are mainly supportive, lacking specific therapies targeting the core pathological mechanisms including neutrophil extracellular traps (NETs)-mediated systemic inflamm...

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Hlavní autoři:	Wenjie Xu, Wenwu Cai, Junyong Wu, Xuyang Hou, Xiaoyan Qi, Zuxing Wei, Yimiao Cheng, Yanwen Zheng, Beibei Cui, Jun He
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-12-01
Edice:	Journal of Nanobiotechnology
Témata:	Severe acute pancreatitis Neutrophil extracellular traps Acinar-ductal metaplasia Mesenchymal stem cell Prussian blue nanoparticle
On-line přístup:	https://doi.org/10.1186/s12951-025-03958-y
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