Nootkatone mitigates periodontal inflammation and reduces alveolar bone loss via Nrf2/HO-1 and NF-κB pathways in rat model of periodontitis

INTRODUCTION: Periodontitis (PD) is a chronic inflammatory disease leading to alveolar bone loss. This study investigated the effect of nootkatone and regulatory mechanism in reducing periodontal inflammation and alveolar bone loss in a rat model. MATERIAL AND METHODS: Twenty male Sprague-Dawley rat...

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Autori principali:	Ye Yin, Zeyu Ma, Peiliang Shi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Via Medica 2024-10-01
Serie:	Folia Histochemica et Cytobiologica
Soggetti:	nootkatone periodontitis alveolar bone loss cytokines oxidative stress NF-κB
Accesso online:	https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/101862
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