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Catalytically inactive lecithin: cholesterol acyltransferase (LCAT) caused by a Gly 30 to Ser mutation in a family with LCAT deficiency

Plasma lecithin:cholesterol acyltransferase (LCAT) plays an important role in early steps of reverse cholesterol transport, i.e., cholesterol efflux from peripheral tissues and cholesterol esterification in HDL. However, structural and functional relationships of LCAT have not been fully elucidated....

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Principais autores: X P Yang, A Inazu, A Honjo, I Koizumi, K Kajinami, J Koizumi, S M Marcovina, J J Albers, H Mabuchi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 1997-03-01
Serier:Journal of Lipid Research
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520372667
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