Biomarkers for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Associated With Hexanucleotide Expansion Mutations in C9orf72

Now that genetic testing can identify persons at risk for developing amyotrophic lateral sclerosis (ALS) many decades before symptoms begin, there is a critical need for biomarkers that signal the onset and progression of degeneration. The search for candidate disease biomarkers in patients with mut...

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Detalhes bibliográficos

Principais autores:	Mary Kay Floeter, Tania F. Gendron
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-12-01
coleção:	Frontiers in Neurology
Assuntos:	C9orf72 cortical thinning diffusion tensor imaging dipeptide repeat proteins functional connectivity motor neuron disease
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fneur.2018.01063/full
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