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Neutrophils in COVID-19: Not Innocent Bystanders

Unusually for a viral infection, the immunological phenotype of severe COVID-19 is characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil-to-lymphocyte ratio correlating with disease severity. Neutrophils are the most abundant immune cell in the bloodstream and com...

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Autori principali: Ellen McKenna, Richard Wubben, Johana M. Isaza-Correa, Ashanty M. Melo, Aisling Ui Mhaonaigh, Niall Conlon, James S. O’Donnell, Clíona Ní Cheallaigh, Tim Hurley, Nigel J. Stevenson, Mark A. Little, Eleanor J. Molloy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-06-01
Serie:Frontiers in Immunology
Soggetti:
neutrophil
COVID-19
SARS-CoV-2
innate immunity
inflammation
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2022.864387/full
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