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Comparative efficacy and safety of ocrelizumab in relapsing-remitting and primary progressive multiple sclerosis: A systematic review and meta-analysis

Abstract Objective This meta-analysis synthesizes evidence from all available randomized trials and observational cohort studies evaluating the efficacy and safety of ocrelizumab compared to placebo or active comparator therapies. Background Ocrelizumab (OCR), a monoclonal antibody targeting CD20-po...

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Principais autores: Adil Nawaz, Arsalan Bakhtiyar, Muhammad Ibrahim Khan, Erum Siddiqui, Elsa Khan, Muhammad Abbas, Muhammad Saad, Muhammad Qasim, Muhammad Taha
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:BMC Neurology
Fag:
Ocrelizumab
Humanized monoclonal antibodies
Multiple sclerosis
Online adgang:https://doi.org/10.1186/s12883-025-04519-4
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