Loss of HPV type 16 E7 restores cGAS-STING responses in human papilloma virus-positive oropharyngeal squamous cell carcinomas cells

Human papilloma viruses (HPV) are the main culprit in cervical and oropharyngeal cancers. HPV positive (+) cancers are regarded as ‘oncogene addicted’, displaying an absolute requirement for the continued expression of the oncogenes for their viability owing their survival, and thus making these gen...

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Detalhes bibliográficos

Principais autores:	Vuk Bortnik, Michelle Wu, Bryan Julcher, Ana Salinas, Iva Nikolic, Kaylene J. Simpson, Nigel AJ. McMillan, Adi Idris
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-08-01
Colecção:	Journal of Microbiology, Immunology and Infection
Assuntos:	cGAS E7 HPV Oral cancer OPSCC STING
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1684118220301675
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