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3204 Renin-Angiotensin System Inhibitors Do Not Improve Survival in Fibrillin-1 Hypomorphic Mice with Established Aortic Aneurysm

OBJECTIVES/SPECIFIC AIMS: Drugs to attenuate aortic growth are usually not initiated in patients with Marfan syndrome until aortic dilation is already present. Therefore, we measured the impact of drugs (the renin-angiotensin system inhibitors losartan and enalapril) on survival and thoracic aortic...

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Autores principales: Mary Burchett Sheppard, Jeff Zheying Chen, Debra L. Rateri, Jessica J. Moorleghen, Mackenzie Weiland, Alan Daugherty
Formato: Artigo
Lenguaje:Inglês
Publicado: Cambridge University Press 2019-03-01
Colección:Journal of Clinical and Translational Science
Acceso en línea:https://www.cambridge.org/core/product/identifier/S2059866119002589/type/journal_article
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