Comparative analysis of the mutational landscape and evolutionary patterns of pancreatic ductal adenocarcinoma metastases in the liver or peritoneum

Background: Pancreatic ductal adenocarcinoma (PDAC) often presents with liver or peritoneal metastases at diagnosis. Despite similar treatment approaches, patient outcomes vary between these metastatic sites. To improve targeted therapies for metastatic PDAC, a comprehensive analysis of the genetic...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Guoliang Yao, Yanfeng Zhu, Chunhui Liu, Yanwen Man, Kefeng Liu, Qin Zhang, Yuan Tan, Qianqian Duan, Dongsheng Chen, Zunguo Du, Yonggang Fan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-08-01
Edice:	Heliyon
Témata:	Liver metastasis Peritoneum metastasis Whole exome sequencing Mutation Clone evolution
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405844024114594
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!