Simultaneous Estimation of Escitalopram and Clonazepam in Tablet Dosage Forms Using HPLC-DAD Method and Optimization of Chromatographic Conditions by Box-Behnken Design

The study aimed to develop a new reverse-phase high-performance liquid chromatography (RP-HPLC) method with diode array detection (DAD) detection for simultaneous estimation of escitalopram (EST) and clonazepam (CZP) in tablet dosage forms with a quality by design (QbD) approach. The chromatographic...

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Principais autores:	Ahmed I. Foudah, Sultan Alshehri, Faiyaz Shakeel, Mohammed H. Alqarni, Tariq M. Aljarba, Prawez Alam
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2022-06-01
叢編:	Molecules
主題:	Box-Behnken design RP-HPLC ICH guidelines stability studies assay
在線閱讀:	https://www.mdpi.com/1420-3049/27/13/4209
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