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Establishment and Validation of a Transdermal Drug Delivery System for the Anti-Depressant Drug Citalopram Hydrobromide

To enhance the bioavailability and antihypertensive effect of the anti-depressant drug citalopram hydrobromide (CTH) we developed a sustained-release transdermal delivery system containing CTH. A transdermal diffusion meter was first used to determine the optimal formulation of the CTH transdermal d...

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Principais autores: Yi-yang Sun, Ya-jing Ni, Run-jia Wang, Zi-cheng Qin, Zhao Liu, Li-hui Xiao, Yan-qiang Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-02-01
coleção:Molecules
Assuntos:
transdermal delivery
citalopram hydrobromide
pharmacokinetics
skin irritation
Acesso em linha:https://www.mdpi.com/1420-3049/29/4/767
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