Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis

Abstract Objective To characterize long-term repopulation of peripheral immune cells following alemtuzumab-induced lymphopenia in relapsing-remitting MS (RRMS), with a focus on regulatory cell types, and to explore associations with clinical outcome measures. Methods The project was designed as a mu...

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Detalhes bibliográficos

Principais autores:	Wendy Gilmore, Brett T. Lund, Peili Li, Alex M. Levy, Eve E. Kelland, Omid Akbari, Susan Groshen, Steven Yong Cen, Daniel Pelletier, Leslie P. Weiner, Adil Javed, Jeffrey E. Dunn, Anthony L. Traboulsee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-06-01
coleção:	Journal of Neuroinflammation
Assuntos:	Multiple sclerosis Alemtuzumab Lymphopenia Lymphocyte repopulation Immune regulation Tolerance
Acesso em linha:	http://link.springer.com/article/10.1186/s12974-020-01847-9
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