EYA4 inhibits hepatocellular carcinoma growth and invasion by suppressing NF-κB-dependent RAP1 transactivation

Abstract Background Our previous studies demonstrated that eyes absent homolog 4 (EYA4), a member of the eye development-related EYA family in Drosophila, is frequently methylated and silenced in hepatocellular carcinoma (HCC) specimens and associated with shorter survival. The current work aimed to...

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Bibliografische Detailangaben

Hauptverfasser:	Shi-Jing Mo, Xun Hou, Xiao-Yi Hao, Jian-Peng Cai, Xin Liu, Wei Chen, Dong Chen, Xiao-Yu Yin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2018-04-01
Schriftenreihe:	Cancer Communications
Schlagworte:	Eyes absent homolog 4 (EYA4) RAS-related protein 1 (RAP1) Nuclear factor-κB (NF-κB) Transactivation Hepatocellular carcinoma
Online-Zugang:	http://link.springer.com/article/10.1186/s40880-018-0276-1
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