Multiaxial rotational loading compromises the transition zone of the intervertebral disc: Ex vivo study using next‐generation bioreactors

Abstract Bioreactors have become indispensable tools in spine research, enabling long‐term intervertebral disc culture under controlled biological and mechanical conditions. Conventional systems are often limited to uniaxial loading, restricting their ability to replicate the complex, multidirection...

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Detalhes bibliográficos

Principais autores:	Amra Šećerović, Aapo Ristaniemi, Francesco Crivelli, Sarah Heub, Mauro Alini, Gilles Weder, Diane Ledroit, Stephen J. Ferguson, Sibylle Grad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-07-01
coleção:	Bioengineering & Translational Medicine
Assuntos:	bioreactors intervertebral disc multiaxial loading transition zone whole organ culture
Acesso em linha:	https://doi.org/10.1002/btm2.70033
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