Comparative investigation of antitumoral effectiveness of Rho-kinase inhibitor Y-27632, pravastatin and atorvastatin in anaplastic thyroid cancer cell culture

Anaplastic thyroid cancer is an aggressive malignancy with a poor prognosis. In metastatic cases instead of treatment alternatives including surgery, radiotherapy, and chemotherapeutic regimens, targeted treatments should be sought for. Statins are 3-hidroxy-3 methylglutaryl-coenzyme A (HMG-CoA) red...

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Главные авторы:	Erdinc Nayir, Selver Cor, Zuhal Mert Altintas, Kansu Buyukafsar, Rukiye Nalan Tiftik, Alper Ata, Ali Arican
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Turkish Society of Oncology 2017-07-01
Серии:	Journal of Oncological Sciences
Предметы:	Anaplastic thyroid cancer ROCK Rho-kinase inhibitor Statin
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2452336417300456
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