Evaluating the Effectiveness of Reference Solvent Solubility Calculations for Binary Mixtures Based on Pure Solvent Solubility: The Case of Phenolic Acids

Predicting the solubility of active pharmaceutical ingredients (APIs) in binary solvent mixtures is a major challenge in formulation science, as physics-based models often fail to capture complex, non-additive mixing effects. This study presents a robust machine learning (ML) framework to overcome t...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Piotr Cysewski, Tomasz Jeliński, Rafal Rozalski, Fabian Lesniewski, Maciej Przybyłek
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2025-11-01
Sarja:	Molecules
Aiheet:	solubility binary solvent reference solvent COSMO-RS machine learning nuSVR
Linkit:	https://www.mdpi.com/1420-3049/30/22/4444
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