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Single-cell mutation identification via phylogenetic inference

Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.

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書目詳細資料
Principais autores: Jochen Singer, Jack Kuipers, Katharina Jahn, Niko Beerenwinkel
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2018-12-01
叢編:Nature Communications
在線閱讀:https://doi.org/10.1038/s41467-018-07627-7
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