Stress-Activated Protein Kinases in Intervertebral Disc Degeneration: Unraveling the Impact of JNK and p38 MAPK

Intervertebral disc degeneration (IDD) is a major cause of lower back pain. The pathophysiological development of IDD is closely related to the stimulation of various stressors, including proinflammatory cytokines, abnormal mechanical stress, oxidative stress, metabolic abnormalities, and DNA damage...

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Autors principals:	Lei Li, Guangzhi Zhang, Zhili Yang, Xuewen Kang
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-03-01
Col·lecció:	Biomolecules
Matèries:	intervertebral disc degeneration JNK p38 MAPK SAPKs stress signaling
Accés en línia:	https://www.mdpi.com/2218-273X/14/4/393
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