Engineering of the Filamentous Fungus Penicillium chrysogenum as Cell Factory for Natural Products

Penicillium chrysogenum (renamed P. rubens) is the most studied member of a family of more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin by Alexander Fleming, this filamentous fungus is used as a commercial β-lactam antibiotic producer. For several decades...

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Hlavní autoři:	Fernando Guzmán-Chávez, Reto D. Zwahlen, Roel A. L. Bovenberg, Arnold J. M. Driessen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-11-01
Edice:	Frontiers in Microbiology
Témata:	Penicillium chrysogenum natural products nonribosomal peptides polyketides gene activation biosynthetic gene clusters
On-line přístup:	https://www.frontiersin.org/article/10.3389/fmicb.2018.02768/full
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