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NOP56 interacts with Fibrarin to regulate the PI3K/AKT signaling pathway and inhibit apoptosis of hepatocellular carcinoma

IntroductionHepatocellular carcinoma (HCC) is a major cause of cancer-related mortality. While *C-myc* is known to drive hepatocarcinogenesis, the roles of its downstream targets remain unclear. NOP56, a conserved nucleolar protein and *C-myc* target, may contribute to HCC progression.MethodsWe anal...

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Wedi'i Gadw mewn:
Prif Awduron: Hongwei Chen, Xinggang Fan, Di Cui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2026-01-01
Cyfres:Frontiers in Oncology
Pynciau:
apoptosis
fibrillarin
hepatocellular carcinoma
NOP56
PI3K/AKT/CREB
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fonc.2025.1728226/full
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