Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies

Infantile onset hereditary spastic paralysis (IAHSP) is a rare neurological disease diagnosed in less than 50 children worldwide. It is transmitted with a recessive pattern and originates from mutations of the <i>ALS2</i> gene, encoding for the protein alsin and involved in differentiation and maint...

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Principais autores:	Matteo Rossi Sebastiano, Giuseppe Ermondi, Kai Sato, Asako Otomo, Shinji Hadano, Giulia Caron
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-10-01
coleção:	Molecules
Assuntos:	infantile onset ascending hereditary spastic paralysis ALS2 virtual screening vitamin K drug repurposing personalized medicine
Acesso em linha:	https://www.mdpi.com/1420-3049/27/20/7063
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