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Model-based stratification of progression along the Alzheimer disease continuum highlights the centrality of biomarker synergies

Abstract Background The progression rates of Alzheimer’s disease (AD) are variable and dynamic, yet the mechanisms that contribute to heterogeneity in progression rates remain ill-understood. Particularly, the role of synergies in pathological processes reflected by biomarkers for amyloid-beta (‘A’)...

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Detalhes bibliográficos
Principais autores: Muhammad Usman Sadiq, Kichang Kwak, Eran Dayan, for the Alzheimer’s Disease Neuroimaging Initiative
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-01-01
coleção:Alzheimer’s Research & Therapy
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Acesso em linha:https://doi.org/10.1186/s13195-021-00941-1
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