Uncovering the roles of Mycobacterium tuberculosis melH in redox and bioenergetic homeostasis: implications for antitubercular therapy

ABSTRACTMycobacterium tuberculosis (Mtb), the pathogenic bacterium that causes tuberculosis, has evolved sophisticated defense mechanisms to counteract the cytotoxicity of reactive oxygen species (ROS) generated within host macrophages during infection. The melH gene in Mtb and Mycobacterium marinum...

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Autors principals:	Yu-Ching Chen, Xinxin Yang, Nan Wang, Nicole S. Sampson
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2024-04-01
Col·lecció:	mSphere
Matèries:	Mycobacterium tuberculosis redox homeostasis ergothioneine aldehyde bioenergetic homeostasis
Accés en línia:	https://journals.asm.org/doi/10.1128/msphere.00061-24
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