Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity.
Macrophages from C57BL/6J (B6) mice restrict growth of the intracellular bacterial pathogen Legionella pneumophila. Restriction of bacterial growth requires caspase-1 and the leucine-rich repeat-containing protein Naip5 (Birc1e). We identified mutants of L. pneumophila that evade macrophage innate i...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2006-03-01
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| Col·lecció: | PLoS Pathogens |
| Accés en línia: | http://europepmc.org/articles/PMC1401497?pdf=render |
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