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Structure of reovirus sigma1 in complex with its receptor junctional adhesion molecule-A.

Viral attachment to specific host receptors is the first step in viral infection and serves an essential function in the selection of target cells. Mammalian reoviruses are highly useful experimental models for studies of viral pathogenesis and show promise as vectors for oncolytics and vaccines. Re...

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Bibliografiske detaljer
Principais autores: Eva Kirchner, Kristen M Guglielmi, Holger M Strauss, Terence S Dermody, Thilo Stehle
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2008-12-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC2588538?pdf=render
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