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Thyroid Hormone-Induced Cytosol-to-Nuclear Translocation of Rat Liver Nrf2 Is Dependent on Kupffer Cell Functioning

L-3,3′,5-triiodothyronine (T3) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redox-sensitive transcription factor mediating cytoprotection. In this work, we studied the role of Kupffer cell respiratory burst activity, a process related to reactive oxygen...

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Váldodahkkit: Luis A. Videla, Pamela Cornejo, Pamela Romanque, Catherine Santibáñez, Iván Castillo, Romina Vargas
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2012-01-01
Ráidu:The Scientific World Journal
Liŋkkat:http://dx.doi.org/10.1100/2012/301494
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