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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

The adenosine-triphosphate-(ATP)-binding cassette (ABC) transporter ABCA7 is a genetic risk factor for Alzheimer’s disease (AD). Defective ABCA7 promotes AD development and/or progression. Unfortunately, ABCA7 belongs to the group of ‘under-studied’ ABC transporters that cannot be addressed by small...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Vigneshwaran Namasivayam, Katja Stefan, Jens Pahnke, Sven Marcel Stefan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Association for the Advancement of Science (AAAS) 2021-01-01
Rangatū:Computational and Structural Biotechnology Journal
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2001037021005006
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