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Second-generation pterocarpanquinones: synthesis and antileishmanial activity

Abstract Background Despite the development of new therapies for leishmaniasis, among the 200 countries or territories reporting to the WHO, 87 were identified as endemic for Tegumentary Leishmaniasis and 75 as endemic for Visceral Leishmaniasis. The identification of antileishmanial drug candidates...

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Hlavní autoři: Viviane dos Santos Faiões, Lívia C. R. M. da Frota, Edézio Ferreira Cunha-Junior, Julio C. F. Barcellos, Thayssa Da Silva, Chaquip Daher Netto, Silvia Amaral Gonçalves Da-Silva, Alcides J. M. da Silva, Paulo R. R. Costa, Eduardo Caio Torres-Santos
Médium: Artigo
Jazyk:Inglês
Vydáno: SciELO 2018-11-01
Edice:Journal of Venomous Animals and Toxins including Tropical Diseases
Témata:
Leishmania
Pterocarpanquinone
LQ-118
Phenotypic assay
Leishmaniasis
Drug discovery
On-line přístup:http://link.springer.com/article/10.1186/s40409-018-0174-7
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