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RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5

Abstract Background Heat-shock molecular chaperone proteins (Hsps) promote the loading of small interfering RNA (siRNA) onto RNA interference (RNAi) effector complexes. While the RNAi process is coupled with heterochromatin assembly in several model organisms, it remains unclear whether the Hsps con...

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Principais autores: Kosuke Okazaki, Hiroaki Kato, Tetsushi Iida, Kaori Shinmyozu, Jun-ichi Nakayama, Yota Murakami, Takeshi Urano
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-06-01
Serier:Epigenetics & Chromatin
Fag:
RNAi
Heterochromatin
Fission yeast
Schizosaccharomyces pombe
Heat-shock molecular chaperons
Hsp90
Online adgang:http://link.springer.com/article/10.1186/s13072-018-0199-8
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